CD4(+) Recent Thymic Emigrants Are Recruited into Granulomas during Leishmania donovani Infection but Have Limited Capacity for Cytokine Production

Recent thymic emigrants (RTEs) represent a source of antigen-naïve T cells that enter the periphery throughout life. However, whether RTEs contribute to the control of chronic parasitic infection and how their potential might be harnessed by therapeutic intervention is currently unclear. Here, we sh...

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Publicado en:PLoS One
Main Authors: Moore, John W. J., Beattie, Lynette, Osman, Mohamed, Owens, Benjamin M. J., Brown, Najmeeyah, Dalton, Jane E., Maroof, Asher, Kaye, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033337/
https://ncbi.nlm.nih.gov/pubmed/27658046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163604
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