Methylation of the minimal promoter of an embryonic globin gene silences transcription in primary erythroid cells
Methylation of cytosines in the dinucleotide CpG has been shown to suppress transcription of a number of tissue-specific genes, yet the precise mechanism is not fully understood. The vertebrate globin genes were among the first examples in which an inverse correlation was shown between CpG methylati...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28373/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9391093/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.25.13724 |
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