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Methylation of the minimal promoter of an embryonic globin gene silences transcription in primary erythroid cells

Methylation of cytosines in the dinucleotide CpG has been shown to suppress transcription of a number of tissue-specific genes, yet the precise mechanism is not fully understood. The vertebrate globin genes were among the first examples in which an inverse correlation was shown between CpG methylati...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Singal, Rakesh, Ferris, Richard, Little, Jane A., Wang, Shu Zhen, Ginder, Gordon D.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The National Academy of Sciences of the USA 1997
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC28373/
https://ncbi.nlm.nih.gov/pubmed/9391093
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