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Th1 transcription factor T-bet regulates the expression of Tim-3
Tim-3 (T cell immunoglobulin, mucin domain)-3 is a membrane protein expressed at late stages of interferon-gamma secreting CD4(+) T helper type 1 (Th1) cell differentiation and constitutively on dendritic cells (DCs). Ligation of Tim-3 on Th1 cells terminates Th1 immune responses. In addition, Tim-3...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2837127/ https://ncbi.nlm.nih.gov/pubmed/20049876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939842 |
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