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Homozygous Deletion of the STK11/LKB1 Locus and the Generation of Novel Fusion Transcripts in Cervical Cancer Cells

The STK11/LKB1 gene encodes a ubiquitously expressed serine/threonine kinase that is mutated in multiple sporadic cancers including non-small cell lung carcinomas, pancreatic cancers, and melanomas. LKB1 affects multiple cellular functions including cell growth, cell cycle progression, metabolism, c...

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Detalhes bibliográficos
Main Authors: McCabe, Michael T., Powell, Doris R., Zhou, Wei, Vertino, Paula M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837085/
https://ncbi.nlm.nih.gov/pubmed/20193846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergencyto.2009.11.017
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