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Aconitase and ATP synthase are targets of malondialdehyde modification and undergo an age-related decrease in activity in mouse heart mitochondria

The main purpose of this study was to identify mitochondrial proteins that exhibit post-translational oxidative modifications during the aging process and to determine the resulting functional alterations. Proteins forming adducts with malondialdehyde (MDA), a product of lipid peroxidation, were ide...

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Detalhes bibliográficos
Main Authors: Yarian, Connie S., Rebrin, Igor, Sohal, Rajindar S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837075/
https://ncbi.nlm.nih.gov/pubmed/15781244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2005.02.135
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