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Aconitase is the main functional target of aging in the citric acid cycle of kidney mitochondria from mice

The activities of the citric acid cycle enzymes were determined in mitochondria isolated from kidneys of relatively young, middle age, and old mice. Aconitase exhibited the most significant decrease in activity with age. The activity of α-ketoglutarate dehydrogenase exhibited a modest decrease in ac...

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Detalhes bibliográficos
Main Authors: Yarian, Connie S., Toroser, Dikran, Sohal, Rajindar S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835517/
https://ncbi.nlm.nih.gov/pubmed/16289253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2005.09.028
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