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Mechanisms of γ-glutamylcysteine ligase regulation

The principal objective of this study was to investigate the mechanisms regulating the activity of γ-glutamylcysteine ligase (GCL; EC 6.3.2.2), the rate limiting enzyme in glutathione biosynthesis. Two phylogenetically divergent species, mouse and the fruitfly, Drosophila melanogaster were used to t...

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Bibliographic Details
Main Authors: Toroser, Dikran, Yarian, Connie S., Orr, William C., Sohal, Rajindar S.
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837077/
https://ncbi.nlm.nih.gov/pubmed/16324789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2005.10.010
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