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Detection and Characterization of Peroxynitrite-Induced Modifications of Tyrosine, Tryptophan, and Methionine Residues by Tandem Mass Spectrometry

Nitration and oxidation of tyrosine, tryptophan, and methionine residues in proteins are potential markers of their interaction with peroxynitrite. This chapter describes the procedure for the detection of these nitro-oxidative modifications by tandem mass spectrometry. The peptide YGDLANWMIPGK, sho...

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Autors principals: Rebrin, Igor, Bregere, Catherine, Gallaher, Timothy K., Sohal, Rajindar S.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820399/
https://ncbi.nlm.nih.gov/pubmed/18554540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0076-6879(08)01215-9
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