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The A+T-rich sequence of the simian virus 40 origin is essential for replication and is involved in bending of the viral DNA.
The origin-promoter region of simian virus 40 contains a 17-base-pair sequence composed exclusively of adenine (A) and thymine (T). We constructed a linker replacement mutant in which this stretch of A's and T's was reduced to 11 base pairs. While not affecting the level of early gene tran...
Bewaard in:
| Gepubliceerd in: | J Virol |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology (ASM)
1987
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283701/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3035231/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.7.2322-2325.1987 |
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