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Inhibition of structural changes in the simian virus 40 core origin of replication by mutation of essential origin sequences.

Mutation of the simian virus 40 (SV40) origin of replication (ori) has revealed the presence of three critical domains needed for DNA replication. The outer two domains, the AT tract and early palindrome element (EP), colocalize with DNA regions that become structurally altered in the presence of th...

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Détails bibliographiques
Publié dans:J Virol
Auteur principal: Borowiec, J A
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289078/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1323692/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.9.5248-5255.1992
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