Functional reciprocity between Na(+) channel Na(v)1.6 and β1 subunits in the coordinated regulation of excitability and neurite outgrowth

Voltage-gated Na(+) channel (VGSC) β1 subunits regulate cell–cell adhesion and channel activity in vitro. We previously showed that β1 promotes neurite outgrowth in cerebellar granule neurons (CGNs) via homophilic cell adhesion, fyn kinase, and contactin. Here we demonstrate that β1-mediated neurite...

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Detalhes bibliográficos
Main Authors: Brackenbury, William J., Calhoun, Jeffrey D., Chen, Chunling, Miyazaki, Haruko, Nukina, Nobuyuki, Oyama, Fumitaka, Ranscht, Barbara, Isom, Lori L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836661/
https://ncbi.nlm.nih.gov/pubmed/20133873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909434107
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