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ISG15 conjugation system targets the viral NS1 protein in influenza A virus–infected cells

ISG15 is an IFN-α/β–induced, ubiquitin-like protein that is conjugated to a wide array of cellular proteins through the sequential action of three conjugation enzymes that are also induced by IFN-α/β. Recent studies showed that ISG15 and/or its conjugates play an important role in protecting cells f...

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Detalhes bibliográficos
Main Authors: Zhao, Chen, Hsiang, Tien-Ying, Kuo, Rei-Lin, Krug, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836655/
https://ncbi.nlm.nih.gov/pubmed/20133869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909144107
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