Structural basis for the sequence-specific recognition of human ISG15 by the NS1 protein of influenza B virus

Interferon-induced ISG15 conjugation plays an important antiviral role against several viruses, including influenza viruses. The NS1 protein of influenza B virus (NS1B) specifically binds only human and nonhuman primate ISG15s and inhibits their conjugation. To elucidate the structural basis for the...

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Bibliografiske detaljer
Main Authors: Guan, Rongjin, Ma, Li-Chung, Leonard, Paul G., Amer, Brendan R., Sridharan, Haripriya, Zhao, Chen, Krug, Robert M., Montelione, Gaetano T.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158222/
https://ncbi.nlm.nih.gov/pubmed/21808041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107032108
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