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Mechanism of amyloid plaque formation suggests an intracellular basis of Aβ pathogenicity
The formation of extracellular amyloid plaques is a common patho-biochemical event underlying several debilitating human conditions, including Alzheimer’s disease (AD). Considerable evidence implies that AD damage arises primarily from small oligomeric amyloid forms of Aβ peptide, but the precise me...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2836607/ https://ncbi.nlm.nih.gov/pubmed/20133839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904532106 |
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