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eIF2α Phosphorylation-Dependent Translation in CA1 Pyramidal Cells Impairs Hippocampal Memory Consolidation without Affecting General Translation

Protein synthesis inhibitor antibiotics are widely used to produce amnesia, and have been recognized to inhibit general or global mRNA translation in the basic translational machinery. For instance, anisomycin interferes with protein synthesis by inhibiting peptidyl transferase or the 80S ribosomal...

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Detalhes bibliográficos
Main Authors: Jiang, Zhihong, Belforte, Juan E., Lu, Yuan, Yabe, Yoko, Pickel, James, Smith, Carolyn Beebe, Je, Hyun-Soo, Lu, Bai, Nakazawa, Kazu
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836228/
https://ncbi.nlm.nih.gov/pubmed/20164343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3971-09.2010
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