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A Fra-1-dependent, matrix metalloproteinase driven EGFR activation promotes human lung epithelial cell motility and invasion

We and others have shown a persistently high induction of Fra-1 transcription factor (a dimeric partner of AP-1) levels by respiratory carcinogens in pulmonary epithelial cells. Fra-1 is frequently overexpressed in various human tumors and cancer cells. We have recently shown that Fra-1 significantl...

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Detalhes bibliográficos
Main Authors: Adiseshaiah, Pavan, Vaz, Michelle, Machireddy, Narsa, Kalvakolanu, Dhananjaya V, Reddy, Sekhar P
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836166/
https://ncbi.nlm.nih.gov/pubmed/18288638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21410
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