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Cardioprotection specific for the G protein G(i2) in chronic adrenergic signaling through β(2)-adrenoceptors

Two subtypes of β-adrenoceptors, β(1) and β(2), mediate cardiac catecholamine effects. These two types differ qualitatively, e.g., regarding G protein coupling and calcium channel stimulation. Transgenic mice overexpressing human β(2)-adrenoceptors survive high-expression levels, unlike mice overexp...

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Detalhes bibliográficos
Main Authors: Foerster, Katharina, Groner, Ferdi, Matthes, Jan, Koch, Walter J., Birnbaumer, Lutz, Herzig, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC283616/
https://ncbi.nlm.nih.gov/pubmed/14612574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1936026100
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