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Agonist-specific activation of the β(2)-adrenoceptor/G(s)-protein and β(2)-adrenoceptor/G(i)-protein pathway in adult rat ventricular cardiomyocytes

1. In rat ventricular cardiomyocytes β(2)-adrenoceptors (AR) couple to G(s)- and G(i)-protein, and evidence has accumulated that β(2)-AR agonists can differentially activate either G(s)- or G(s)- and G(i)-protein. 2. In this study, in isolated adult rat ventricular cardiomyocytes, we assessed the ef...

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Detalhes bibliográficos
Main Authors: Pönicke, Klaus, Gröner, Ferdinand, Heinroth-Hoffmann, Ingrid, Brodde, Otto-Erich
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751514/
https://ncbi.nlm.nih.gov/pubmed/16474418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706674
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