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Regulation of voltage-gated calcium channel activity by the Rem and Rad GTPases

Rem, Rem2, Rad, and Gem/Kir (RGK) represent a distinct GTPase family with largely unknown physiological functions. We report here that both Rem and Rad bind directly to Ca(2+) channel β-subunits (Ca(V)β) in vivo. No calcium currents are recorded from human embryonic kidney 293 cells coexpressing the...

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Autors principals: Finlin, Brian S., Crump, Shawn M., Satin, Jonathan, Andres, Douglas A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC283615/
https://ncbi.nlm.nih.gov/pubmed/14623965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2437756100
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