Excitotoxicity, calcium and mitochondria: a triad in synaptic neurodegeneration
Abstract Glutamate is the most commonly engaged neurotransmitter in the mammalian central nervous system, acting to mediate excitatory neurotransmission. However, high levels of glutamatergic input elicit excitotoxicity, contributing to neuronal cell death following acute brain injuries such as stro...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BMC
2022-01-01
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| Colección: | Translational Neurodegeneration |
| Materias: | |
| Acceso en línea: | https://doi.org/10.1186/s40035-021-00278-7 |
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