Excitatory Dendritic Mitochondrial Calcium Toxicity: Implications for Parkinson’s and Other Neurodegenerative Diseases

Dysregulation of calcium homeostasis has been linked to multiple neurological diseases. In addition to excitotoxic neuronal cell death observed following stroke, a growing number of studies implicate excess excitatory neuronal activity in chronic neurodegenerative diseases. Mitochondria function to...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Manish Verma, Zachary Wills, Charleen T. Chu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2018-08-01
Edice:	Frontiers in Neuroscience
Témata:	mitochondrial calcium uniporter PINK1 LRRK2 calcium overload Parkinson Disease/Lewy body dementia Alzheimer Disease
On-line přístup:	https://www.frontiersin.org/article/10.3389/fnins.2018.00523/full
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!