Mys Protein Regulates Protein Kinase A Activity by Interacting with Regulatory Type Iα Subunit during Vertebrate Development

During embryonic development, protein kinase A (PKA) plays a key role in cell fate specification by antagonizing the Hedgehog (Hh) signaling pathway. However, the mechanism by which PKA activity is regulated remains unknown. Here we show that the Misty somites (Mys) protein regulates the level of PK...

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Bibliographische Detailangaben
Hauptverfasser: Kotani, Tomoya, Iemura, Shun-ichiro, Natsume, Tohru, Kawakami, Koichi, Yamashita, Masakane
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836113/
https://ncbi.nlm.nih.gov/pubmed/20018846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.070995
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