Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by δ subunit-containing GABA(A) receptors
Neuroactive steroids are potent modulators of γ-aminobutyric acid type A receptors (GABA(A)Rs), and their behavioral effects are generally viewed in terms of altered inhibitory synaptic transmission. Here we report that, at concentrations known to occur in vivo, neuroactive steroids specifically enh...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283610/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14623958/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2435457100 |
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