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Potassium Channel Silencing by Constitutive Endocytosis and Intracellular Sequestration
Tandem of P domains in a weak inwardly rectifying K(+) channel 1 (TWIK1) is a K(+) channel that produces unusually low levels of current. Replacement of lysine 274 by a glutamic acid (K274E) is associated with stronger currents. This mutation would prevent conjugation of a small ubiquitin modifier p...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2836085/ https://ncbi.nlm.nih.gov/pubmed/19959478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.078535 |
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