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FoxO Proteins Mediate Hypoxic Induction of Connective Tissue Growth Factor in Endothelial Cells
Hypoxia, a driving force in neovascularization, promotes alterations in gene expression mediated by hypoxia-inducible factor (HIF)-1α. Connective tissue growth factor (CTGF, CCN2) is a modulator of endothelial cell growth and migration, but its regulation by hypoxia is poorly understood. Therefore,...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2836037/ https://ncbi.nlm.nih.gov/pubmed/20018872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.049650 |
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