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FoxO Proteins Mediate Hypoxic Induction of Connective Tissue Growth Factor in Endothelial Cells

Hypoxia, a driving force in neovascularization, promotes alterations in gene expression mediated by hypoxia-inducible factor (HIF)-1α. Connective tissue growth factor (CTGF, CCN2) is a modulator of endothelial cell growth and migration, but its regulation by hypoxia is poorly understood. Therefore,...

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Bibliografiska uppgifter
Huvudupphovsmän: Samarin, Jana, Wessel, Julia, Cicha, Iwona, Kroening, Sven, Warnecke, Christina, Goppelt-Struebe, Margarete
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836037/
https://ncbi.nlm.nih.gov/pubmed/20018872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.049650
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