Regulation of Virus-triggered Signaling by OTUB1- and OTUB2-mediated Deubiquitination of TRAF3 and TRAF6

Ubiquitination and deubiquitination have emerged as critical post-translational regulatory mechanisms for activation or attenuation of the virus-triggered type I interferon (IFN) induction pathways. In this study, we identified two deubiquitinating enzymes, OTUB1 and OTUB2, as negative regulators of...

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Autori principali: Li, Shu, Zheng, Hao, Mao, Ai-Ping, Zhong, Bo, Li, Ying, Liu, Yu, Gao, Yan, Ran, Yong, Tien, Po, Shu, Hong-Bing
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836033/
https://ncbi.nlm.nih.gov/pubmed/19996094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.074971
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