Solution structure of the Drosha double-stranded RNA-binding domain

BACKGROUND: Drosha is a nuclear RNase III enzyme that initiates processing of regulatory microRNA. Together with partner protein DiGeorge syndrome critical region 8 (DGCR8), it forms the Microprocessor complex, which cleaves precursor transcripts called primary microRNA to produce hairpin precursor...

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Bibliographic Details
Main Authors: Mueller, Geoffrey A, Miller, Matthew T, DeRose, Eugene F, Ghosh, Mahua, London, Robert E, Hall, Traci M Tanaka
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836000/
https://ncbi.nlm.nih.gov/pubmed/20226070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-907X-1-2
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