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Effect of Modulation of hnRNP L Levels on the Decay of bcl-2 mRNA in MCF-7 Cells

It has been shown that CA repeats in the 3'-untranslated region (UTR) of bcl-2 mRNA contribute the constitutive decay of bcl-2 mRNA and that hnRNP L (heterogenous nuclear ribonucleoprotein L) interacts with CA repeats in the 3'-UTR of bcl-2 mRNA, both in vitro and in vivo. The aim of this...

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Detalhes bibliográficos
Main Authors: Lim, Mi-Hyun, Lee, Dong-Hyoung, Jung, Seung Eun, Youn, Dong-Ye, Park, Chan Sun, Lee, Jeong-Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Physiological Society and The Korean Society of Pharmacology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835978/
https://ncbi.nlm.nih.gov/pubmed/20221275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2010.14.1.15
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