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Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase
Maintenance of genome integrity is of critical importance to cells. To identify key regulators of genomic integrity, we screened a human cell line with a kinome small interfering RNA library. WEE1, a major regulator of mitotic entry, and CHK1 were among the genes identified. Both kinases are importa...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2835936/ https://ncbi.nlm.nih.gov/pubmed/20194642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200905059 |
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