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Murine cytomegalovirus paralyzes macrophages by blocking IFNγ-induced promoter assembly
Macrophages (Mϕ) are activated by IFNγ and are important cellular targets for infection by human and murine cytomegalovirus (MCMV), making it advantageous for CMVs to block IFNγ-induced Mϕ differentiation. We found that MCMV infection inhibited IFNγ regulation of many genes in Mϕ. MCMV infection blo...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC283588/ https://ncbi.nlm.nih.gov/pubmed/14614150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1835673100 |
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