Sirtuin1-p53, forkhead box O3a, p38 and post-infarct cardiac remodeling in the spontaneously diabetic Goto-Kakizaki rat

BACKGROUND: Diabetes is associated with changes in myocardial stress-response pathways and is recognized as an independent risk factor for cardiac remodeling. Using spontaneously diabetic Goto Kakizaki rats as a model of type 2 DM we investigated whether post-translational modifications in the Akt -...

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Autores principales: Vahtola, Erik, Louhelainen, Marjut, Forstén, Hanna, Merasto, Saara, Raivio, Johanna, Kaheinen, Petri, Kytö, Ville, Tikkanen, Ilkka, Levijoki, Jouko, Mervaala, Eero
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2010
Materias:
Original investigation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835668/
https://ncbi.nlm.nih.gov/pubmed/20105289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-9-5
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