Effects of levosimendan on cardiac remodeling and cardiomyocyte apoptosis in hypertensive Dahl/Rapp rats

BACKGROUND AND PURPOSE: Progression of heart failure in hypertensive Dahl rats is associated with cardiac remodeling and increased cardiomyocyte apoptosis. This study was conducted to study whether treatment with a novel inotropic vasodilator compound, levosimendan, could prevent hypertension-induce...

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Detalhes bibliográficos
Main Authors: Louhelainen, M, Vahtola, E, Kaheinen, P, Leskinen, H, Merasto, S, Kytö, V, Finckenberg, P, Colucci, W S, Levijoki, J, Pollesello, P, Haikala, H, Mervaala, E M A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013885/
https://ncbi.nlm.nih.gov/pubmed/17325658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707157
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