Angiotensin II Induces Connective Tissue Growth Factor Gene Expression via Calcineurin-Dependent Pathways

Connective tissue growth factor (CTGF) is a polypeptide implicated in the extracellular matrix synthesis. Previous studies have provided evidence that angiotensin II (Ang II) promotes collagen synthesis and regulates collagen degradation. We investigated whether or not CTGF mediates the profibrotic...

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Autori principali: Finckenberg, Piet, Inkinen, Kaija, Ahonen, Juhani, Merasto, Saara, Louhelainen, Marjut, Vapaatalo, Heikki, Müller, Dominik, Ganten, Detlev, Luft, Friedrich, Mervaala, Eero
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868168/
https://ncbi.nlm.nih.gov/pubmed/12819040
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