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Comparison of enalapril and valsartan in cyclosporine A-induced hypertension and nephrotoxicity in spontaneously hypertensive rats on high-sodium diet

1. We compared the effects of the angiotensin converting enzyme (ACE) inhibitor enalapril and the angiotensin AT(1) receptor antagonist valsartan in cyclosporine A (CsA)-induced hypertension and nephrotoxicity in spontaneously hypertensive rats (SHR). 2. SHR (8–9 weeks old) on high-sodium diet were...

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Bibliographic Details
Main Authors: Lassila, Markus, Finckenberg, Piet, Pere, Anna-Kaisa, Krogerus, Leena, Ahonen, Juhani, Vapaatalo, Heikki, Nurminen, Marja-Leena
Format: Artigo
Language:Inglês
Published: 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572182/
https://ncbi.nlm.nih.gov/pubmed/10903974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703422
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