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Glatiramer acetate-specific T cells in the brain express T helper 2/3 cytokines and brain-derived neurotrophic factor in situ

The ability of a remedy to modulate the pathological process in the target organ is crucial for its therapeutic activity. Glatiramer acetate (GA, Copaxone, Copolymer 1), a drug approved for the treatment of multiple sclerosis, induces regulatory T helper 2/3 cells that penetrate the CNS. Here we inv...

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Sonraí Bibleagrafaíochta
Main Authors: Aharoni, Rina, Kayhan, Basak, Eilam, Raya, Sela, Michael, Arnon, Ruth
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2003
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC283562/
https://ncbi.nlm.nih.gov/pubmed/14614135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2336171100
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