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The immunomodulator glatiramer acetate augments the expression of neurotrophic factors in brains of experimental autoimmune encephalomyelitis mice

Neurotrophins (NTs) such as BDNF, NT-3, and NT-4 are important modulators of neuronal function and survival. Their expression in the CNS after various insults is thus of major therapeutic consequence. Glatiramer acetate [(GA) Copaxone], an approved drug for the treatment of multiple sclerosis, has b...

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Main Authors: Aharoni, Rina, Eilam, Raya, Domev, Hagit, Labunskay, Galya, Sela, Michael, Arnon, Ruth
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1323190/
https://ncbi.nlm.nih.gov/pubmed/16365293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509438102
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