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The C-terminal domains of ADAMTS-4 and ADAMTS-5 promote association with N-TIMP-3

We investigated whether the affinity of tissue inhibitor of metalloproteinases (TIMP)-3 for adamalysins with thrombospondin motifs (ADAMTS)-4 and ADAMTS-5 is affected by the non-catalytic ancillary domains of the enzymes. For this purpose, we first established a novel method of purifying recombinant...

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Dettagli Bibliografici
Autori principali: Troeberg, Linda, Fushimi, Kazunari, Scilabra, Simone D., Nakamura, Hiroyuki, Dive, Vincent, Thøgersen, Ida B., Enghild, Jan J., Nagase, Hideaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835468/
https://ncbi.nlm.nih.gov/pubmed/19643179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2009.07.005
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