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Pharmacologic Inhibition of Phospholipid Transfer Protein Activity Reduces Apolipoprotein-B Secretion from Hepatocytes

Phospholipid transfer protein (PLTP) plays an important role in atherogenesis, and its function goes well beyond that of transferring phospholipids between lipoprotein particles. Previous studies showed that genetic deficiency of PLTP in mice causes a substantially impaired hepatic secretion of apol...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Luo, Yi, Shelly, Lorraine, Sand, Thomas, Reidich, Benjamin, Chang, George, MacDougall, Mary, Peakman, Marie-Claire, Jiang, Xian-Cheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835446/
https://ncbi.nlm.nih.gov/pubmed/19933370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.161232
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