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Pharmacologic Inhibition of Phospholipid Transfer Protein Activity Reduces Apolipoprotein-B Secretion from Hepatocytes

Phospholipid transfer protein (PLTP) plays an important role in atherogenesis, and its function goes well beyond that of transferring phospholipids between lipoprotein particles. Previous studies showed that genetic deficiency of PLTP in mice causes a substantially impaired hepatic secretion of apol...

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Detalhes bibliográficos
Main Authors: Luo, Yi, Shelly, Lorraine, Sand, Thomas, Reidich, Benjamin, Chang, George, MacDougall, Mary, Peakman, Marie-Claire, Jiang, Xian-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835446/
https://ncbi.nlm.nih.gov/pubmed/19933370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.161232
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