Activation of Nerve Growth Factor-Induced Bα by Methylene-Substituted Diindolylmethanes in Bladder Cancer Cells Induces Apoptosis and Inhibits Tumor Growth

Nerve growth factor-induced B (NGFI-B) genes are orphan nuclear receptors, and NGFI-Bα (Nur77, TR3) is overexpressed in bladder tumors and bladder cancer cells compared with nontumorous bladder tissue. 1,1-Bis(3′-indolyl)-1-(p-methoxyphenyl)-methane (DIM-C-pPhOCH(3)) and 1,1-bis(3′-indolyl)-1-(p-phe...

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Hlavní autoři: Dae Cho, Sung, Lee, Syng-Ook, Chintharlapalli, Sudhakar, Abdelrahim, Maen, Khan, Shaheen, Yoon, Kyungsil, Kamat, Ashish M., Safe, Stephen
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835419/
https://ncbi.nlm.nih.gov/pubmed/20023005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.061143
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