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Nuclear translocation of 3′-phosphoinositide-dependent protein kinase 1 (PDK-1): A potential regulatory mechanism for PDK-1 function

3′-Phosphoinositide-dependent protein kinase 1 (PDK-1) phosphorylates and activates members of the AGC protein kinase family and plays an important role in the regulation of cell survival, differentiation, and proliferation. However, how PDK-1 is regulated in cells remains elusive. In this study, we...

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Bibliografiske detaljer
Main Authors: Lim, Mei A., Kikani, Chintan K., Wick, Michael J., Dong, Lily Q.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC283536/
https://ncbi.nlm.nih.gov/pubmed/14623982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2335486100
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