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Membrane cholesterol, lateral mobility, and the phosphatidylinositol 4,5-bisphosphate-dependent organization of cell actin

Responses to cholesterol depletion are often taken as evidence of a role for lipid rafts in cell function. Here, we show that depletion of cell cholesterol has global effects on cell and plasma membrane architecture and function. The lateral mobility of membrane proteins is reduced when cell cholest...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Kwik, Jeanne, Boyle, Sarah, Fooksman, David, Margolis, Leonid, Sheetz, Michael P., Edidin, Michael
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283529/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14612561/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2336102100
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