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Membrane cholesterol, lateral mobility, and the phosphatidylinositol 4,5-bisphosphate-dependent organization of cell actin

Responses to cholesterol depletion are often taken as evidence of a role for lipid rafts in cell function. Here, we show that depletion of cell cholesterol has global effects on cell and plasma membrane architecture and function. The lateral mobility of membrane proteins is reduced when cell cholest...

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出版年:Proc Natl Acad Sci U S A
主要な著者: Kwik, Jeanne, Boyle, Sarah, Fooksman, David, Margolis, Leonid, Sheetz, Michael P., Edidin, Michael
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283529/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14612561/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2336102100
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