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Suppression of Cancer Growth by Nonviral Gene Therapy Based on a Novel Reactive Oxygen Species-responsive Promoter

Increased reactive oxygen species (ROS) production has been reported as a distinctive feature of different pathologies including cancer. Therefore, we assessed whether increased ROS production in the cancer microenvironment could be selectively exploited to develop a selective anticancer therapy. Fo...

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Detalhes bibliográficos
Main Authors: Policastro, Lucía L, Ibañez, Irene L, Durán, Hebe A, Soria, Gastón, Gottifredi, Vanesa, Podhajcer, Osvaldo L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835249/
https://ncbi.nlm.nih.gov/pubmed/19436270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.103
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