Intratracheal Gene Transfer of Adrenomedullin Using Polyplex Nanomicelles Attenuates Monocrotaline-induced Pulmonary Hypertension in Rats

Pulmonary arterial hypertension (PAH) is a life-threatening disease characterized by progressive PAH and right ventricular failure. Despite recent advances in therapeutic approaches using prostanoids, endothelin antagonists, and so on, PAH remains a challenging condition. To develop a novel therapeu...

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Détails bibliographiques
Auteurs principaux: Harada-Shiba, Mariko, Takamisawa, Itaru, Miyata, Kanjiro, Ishii, Takehiko, Nishiyama, Nobuhiro, Itaka, Keiji, Kangawa, Kenji, Yoshihara, Fumiki, Asada, Yujiro, Hatakeyama, Kinta, Nagaya, Noriya, Kataoka, Kazunori
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2009
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835223/
https://ncbi.nlm.nih.gov/pubmed/19337232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.63
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