Autologous Bone Marrow Stromal Cells Genetically Engineered to Secrete an IGF-I Receptor Decoy Prevent the Growth of Liver Metastases

Liver metastases respond poorly to current therapy and remain a frequent cause of cancer-related mortality. We reported previously that tumor cells expressing a soluble form of the insulin-like growth factor-I receptor (sIGFIR) lost the ability to metastasize to the liver. Here, we sought to develop...

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Bibliographic Details
Main Authors: Wang, Ni, Fallavollita, Lucia, Nguyen, Long, Burnier, Julia, Rafei, Moutih, Galipeau, Jacques, Yakar, Shoshana, Brodt, Pnina
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2009
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835215/
https://ncbi.nlm.nih.gov/pubmed/19367255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.82
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