Mesenchymal Stromal Cells Engineered to Express Erythropoietin Induce Anti-erythropoietin Antibodies and Anemia in Allorecipients

Autologous bone marrow mesenchymal stromal cells (MSCs) have been successfully used for the delivery of erythropoietin (EPO) in murine models of anemia and myocardial infarction. For clinical applications where a transient effect would be adequate, such as myocardial infarction, the use of EPO-engin...

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Detalhes bibliográficos
Main Authors: Campeau, Philippe M, Rafei, Moutih, François, Moïra, Birman, Elena, Forner, Kathy-Ann, Galipeau, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835073/
https://ncbi.nlm.nih.gov/pubmed/19088705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.270
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