Enhancement of Oncolytic Properties of Recombinant Newcastle Disease Virus Through Antagonism of Cellular Innate Immune Responses

Newcastle disease virus (NDV) has been previously shown to possess oncolytic activity, causing specific lysis of cancerous but not normal cells. Here we show that despite these findings, the oncolytic efficiency of naturally occurring NDV strains can still be relatively low, as many tumors exhibit s...

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Sonraí Bibleagrafaíochta
Main Authors: Zamarin, Dmitriy, Martínez-Sobrido, Luis, Kelly, Kaitlyn, Mansour, Mena, Sheng, Gang, Vigil, Adam, García-Sastre, Adolfo, Palese, Peter, Fong, Yuman
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2009
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Original Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835121/
https://ncbi.nlm.nih.gov/pubmed/19209145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.286
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